In genetic pathology, (sometimes written as Y1188X ) refers to a specific "nonsense mutation" in the Desmoplakin (DSP) gene.
The string "1188x" frequently appears in mathematical modeling and algebraic expressions: In genetic pathology, (sometimes written as Y1188X )
: Photomicrographs of tissue samples, such as those used to identify fungal diseases like chromoblastomycosis , may be viewed at exactly 1188x magnification to reveal distinctive histopathologic changes in the skin. File:Chromoblastomycosis06.jpeg - wikidoc 188th amino acid (Tyrosine)
: It is associated with Arrhythmogenic Right Ventricular Dysplasia (ARVD) , a heart condition that can lead to life-threatening arrhythmias, as well as cutaneous (skin) abnormalities. 2. Mathematics: Regression & Polynomials resulting in a truncated
: The "X" denotes a stop codon. This mutation causes the protein-building process to terminate early at the 1,188th amino acid (Tyrosine), resulting in a truncated, non-functional protein.